Knee pain affects walking. Climbing up stairs and down stairs is a challenge. It may interfere with physical activity and even keep you up at night. Osteoarthritis is one of the common causes. Medical doctors are striving to avoid continued use of opioids and other pain medications. National Guidelines for Physicians recommends acupuncture as a first line defense against knee pain. On the basis of the findings of the 10 randomized, controlled trials, there is evidence that acupuncture is an effective treatment of pain and physical dysfunction associated with osteoarthritis of the knee. Acupuncture is anti-inflammatory, and releases endogenous opioid endorphins—the body’s own natural pain-relieving chemicals.